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(11)

EP 4 565 608 A2

(12)

(88) Date of publication A3: 16.05.2024 (43) Date of publication: 11.06.2025 Bulletin 2025/24 (21) Application number: 23850993.9 (22) Date of filing: 04.08.2023

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61K 9/08(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/47; C07K 2319/00; A61K 39/39591; C07K 2317/31; C07K 16/18 (86) International application number: PCT/US2023/071667 (87) International publication number: WO 2024/031049 (08.02.2024 Gazette 2024/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 05.08.2022 US 202263395417 P (71) Applicant: Alexion Pharmaceuticals, Inc. Boston, MA 02210 (US)	(72) Inventors: YANG, Teng-Chieh Boston, MA 02210 (US) KANG, Huan Boston, MA 02210 (US) RADHAKRISHNAN, Vinay Boston, MA 02210 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)