(19)

(11)

EP 4 568 616 A2

(12)

(88) Date of publication A3: 02.05.2024 (43) Date of publication: 18.06.2025 Bulletin 2025/25 (21) Application number: 23853506.6 (22) Date of filing: 09.08.2023

(51) International Patent Classification (IPC):  A61F 2/07(2013.01) A61L 31/00(2006.01) A61F 2/86(2013.01) (52) Cooperative Patent Classification (CPC): A61F 2/07; A61F 2002/075; A61F 2250/0067; A61F 2002/9528 (86) International application number: PCT/US2023/071910 (87) International publication number: WO 2024/036199 (15.02.2024 Gazette 2024/07)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 09.08.2022 US 202263396492 P 09.08.2022 US 202263396552 P (71) Applicant: The General Hospital Corporation Boston, MA 02114 (US)	(72) Inventors: SINGH, Varun Boston, MA 02114 (US) GASTON, Brandon Boston, MA 02114 (US) (74) Representative: Maiwald GmbH  Engineering Elisenhof Elisenstrasse 3 80335 München 80335 München (DE)