(19)

(11)

EP 4 568 700 A2

(12)

(88) Date of publication A3: 28.03.2024 (43) Date of publication: 18.06.2025 Bulletin 2025/25 (21) Application number: 23769038.3 (22) Date of filing: 08.08.2023

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/28(2006.01) A61P 35/00(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2809; C07K 16/2851; A61K 2039/505; C07K 2317/31; C07K 16/28; A61P 35/00; A61K 39/395; C07K 2317/92; C07K 2317/76 (86) International application number: PCT/US2023/071829 (87) International publication number: WO 2024/036139 (15.02.2024 Gazette 2024/07)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 09.08.2022 US 202263396536 P (71) Applicant: QLSF Biotherapeutics, Inc. South San Francisco, California 94080 (US)	(72) Inventors: JIN, Mengyao South San Francisco, California 94080 (US) CHEN, Shihao South San Francisco, California 94080 (US) (74) Representative: Lau, Sarah Jane et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)