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(11)

EP 4 568 992 A1

(12)

(43) Date of publication: 18.06.2025 Bulletin 2025/25 (21) Application number: 23757681.4 (22) Date of filing: 09.08.2023

(51) International Patent Classification (IPC):  C07K 14/725(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/7051; C07K 2319/03; A61K 2239/10; A61K 2239/17; A61K 2239/13; A61P 35/00; C12N 2510/00; C12N 5/0636; C07K 16/2803; C07K 2317/55; C07K 14/70507; C12N 2501/53; C12N 2501/515; C12N 2501/51; A61K 40/4211; A61K 40/11; A61K 40/31 (86) International application number: PCT/GB2023/052105 (87) International publication number: WO 2024/033642 (15.02.2024 Gazette 2024/07)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 09.08.2022 GB 202211637 (71) Applicant: Oxford University Innovation Limited Oxford, OX2 0JB (GB)	(72) Inventor: DUSHEK, Omer Oxford Oxfordshire OX4 1QL (GB) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)