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(11)

EP 4 572 777 A1

(12)

(43) Date of publication: 25.06.2025 Bulletin 2025/26 (21) Application number: 23751260.3 (22) Date of filing: 25.07.2023

(51) International Patent Classification (IPC):  A61K 36/708(2006.01) A61K 36/258(2006.01) A61P 1/02(2006.01) A61K 36/886(2006.01) A61Q 11/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 1/02; A61K 36/708; A61K 36/886; A61K 36/258; A61Q 11/00; A61K 8/9789; A61K 8/9794   C-Sets: A61K 36/708, A61K 2300/00; A61K 36/886, A61K 2300/00; A61K 36/258, A61K 2300/00; (86) International application number: PCT/EP2023/070540 (87) International publication number: WO 2024/037841 (22.02.2024 Gazette 2024/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 15.08.2022 EP 22190349 (71) Applicant: UNIVERSITÄTSmedizin der Johannes Gutenberg- Universität Mainz 55131 Mainz (DE)	(72) Inventors: MÜLLER-HEUPT, Lena Katharina 64572 Büttelborn (DE) WIESMANN, Nadine 55129 Mainz (DE) SCHRÖDER, Sofia Franziska 55131 Mainz (DE) (74) Representative: Patentanwälte Dr. Keller, Schwertfeger Partnerschaft mbB  Westring 17 76829 Landau 76829 Landau (DE)