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EP 4 573 093 A1

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(43) Date of publication: 25.06.2025 Bulletin 2025/26 (21) Application number: 23768073.1 (22) Date of filing: 18.08.2023

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) C07D 495/04(2006.01) A61P 35/00(2006.01) C07D 491/10(2006.01) A61K 31/437(2006.01) A61P 35/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04; A61P 35/00; A61P 35/04; C07D 491/10; C07D 495/04 (86) International application number: PCT/US2023/030599 (87) International publication number: WO 2024/039861 (22.02.2024 Gazette 2024/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 19.08.2022 US 202263399276 P (71) Applicant: Olema Pharmaceuticals, Inc. San Francisco, CA 94107 (US)

(72) Inventors: HEARN, Brian R. San Francisco, California 94107 (US) CAO, Xufeng San Francisco, California 94107 (US) YEGHIKYAN, David San Francisco, California 94107 (US) SHETTY, Rupa S. San Francisco, California 94107 (US) RICH, Brian San Francisco, California 94107 (US) CHAWLA, Reena San Francisco, California 94107 (US) HEERDING, Dirk A. San Francisco, California 94107 (US) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)