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(11)

EP 4 573 110 A1

(12)

(43) Date of publication: 25.06.2025 Bulletin 2025/26 (21) Application number: 23772061.0 (22) Date of filing: 18.08.2023

(51) International Patent Classification (IPC):  C07K 14/52(2006.01) A61P 35/00(2006.01) C07K 16/28(2006.01) A61K 38/19(2006.01) C07K 14/715(2006.01) C07K 14/555(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/7156; C07K 2319/00; C07K 2319/30; C07K 14/555; C07K 2319/50; C07K 2317/52; C07K 16/2818; A61K 38/00 (86) International application number: PCT/US2023/072512 (87) International publication number: WO 2024/040247 (22.02.2024 Gazette 2024/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 18.08.2022 US 202263399040 P 15.11.2022 US 202263383804 P 24.01.2023 US 202363481303 P (71) Applicant: Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591 (US)

(72) Inventors: WEICK, Eva-Maria Tarrytown, New York 10591 (US) BLOCH, Nicolin Tarrytown, New York 10591 (US) GARG, Vidur Tarrytown, New York 10591 (US) ULLMAN, Erica Tarrytown, New York 10591 (US) ZHANG, Tong Tarrytown, New York 10591 (US) LIN, Chia-Yang Tarrytown, New York 10591 (US) WU, Jiaxi Tarrytown, New York 10591 (US) SMITH, Eric Tarrytown, New York 10591 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)