(19)
(11) EP 4 573 123 A1

(12)

(43) Date of publication:
25.06.2025 Bulletin 2025/26

(21) Application number: 23757605.3

(22) Date of filing: 16.08.2023
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 2039/505; A61P 35/00; C07K 16/2803; C07K 2317/24; C07K 2317/34; C07K 2317/92; A61K 47/6831; A61K 47/6849
(86) International application number:
PCT/EP2023/072528
(87) International publication number:
WO 2024/038075 (22.02.2024 Gazette 2024/08)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 18.08.2022 EP 22191026

(71) Applicants:
  • ELI LILLY AND CO.
    Indianapolis, IN 46285 (US)
  • Université d'Aix Marseille
    13007 Marseille (FR)
  • INSERM (Institut National de la Santé et de la Recherche Médicale)
    75013 Paris (FR)
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
    75016 Paris (FR)
  • Institut Jean Paoli & Irène Calmettes
    13009 Marseille (FR)

(72) Inventors:
  • ELANDS, Jack
    1190 Forest (BE)
  • L'HOSPICE, Florence
    29770 Primelin (FR)
  • PRÉVILLE, Xavier
    06330 Roquefort les Pins (FR)
  • OLIVE, Daniel
    13009 Marseille (FR)
  • LOPEZ, Marc
    13009 Marseille (FR)

(74) Representative: Eli Lilly and Company Limited 
8 Arlington Square West Downshire Way
Bracknell Berkshire RG12 1PU
Bracknell Berkshire RG12 1PU (GB)

   


(54) HUMANIZED ANTI-NECTIN-4 ANTIBODIES