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EP 4 577 520 A1

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(43) Date of publication: 02.07.2025 Bulletin 2025/27 (21) Application number: 23858332.2 (22) Date of filing: 25.08.2023

(51) International Patent Classification (IPC):  C07C 233/47(2006.01) A61K 31/7105(2006.01) C07C 233/18(2006.01) C07C 271/22(2006.01) A61K 9/51(2006.01) A61K 48/00(2006.01) C07C 233/52(2006.01) C07D 207/12(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/7105; C07D 207/12; C12N 15/88; A61K 48/0041; A61K 48/0075; A61K 9/5123; A61K 9/0019; C08G 65/3331; C08G 65/3332; C08G 65/3312; A61K 31/713; C08G 65/2621; C08G 65/2615 (86) International application number: PCT/US2023/072878 (87) International publication number: WO 2024/044728 (29.02.2024 Gazette 2024/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 26.08.2022 US 202263373649 P 30.06.2023 US 202363511515 P (71) Applicant: Renagade Therapeutics Management Inc. Cambridge, Massachusetts 02139 (US)	(72) Inventors: JAYARAMAN, Muthusamy Cambridge, Massachusetts 02139 (US) SANKARAN, Ganapathy Subramanian Cambridge, Massachusetts 02139 (US) (74) Representative: Schlich  9 St Catherine's Road Littlehampton West Sussex BN17 5HS West Sussex BN17 5HS (GB)