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EP 4 577 526 A1

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(43) Date of publication: 02.07.2025 Bulletin 2025/27 (21) Application number: 23858210.0 (22) Date of filing: 21.08.2023

(51) International Patent Classification (IPC):  C07D 257/02(2006.01) A61K 51/10(2006.01) C07F 9/6524(2006.01) C07K 16/30(2006.01) A61K 49/16(2006.01) A61P 35/00(2006.01) C07K 5/103(2006.01) C07K 16/32(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07D 257/02; C07F 9/6524; C07K 16/30; C07K 16/32; C07D 213/79; C07B 59/008; C07K 2317/52; C07K 2317/569; C07K 2317/64; C07K 2319/00; C07K 16/18; C07K 2317/33; C07K 2317/71; C07K 2317/77; C07K 2317/94; C07K 2317/92; C07K 2317/22; A61K 51/1093; A61K 51/1096; A61K 51/1045; C07K 5/06052; C07K 5/0812; C07K 5/1008 (86) International application number: PCT/US2023/072585 (87) International publication number: WO 2024/044549 (29.02.2024 Gazette 2024/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 22.08.2022 US 202263373183 P (71) Applicant: Abdera Therapeutics Inc. South San Francisco, California 94080 (US)	(72) Inventors: ABRAMS, Michael J. San Francisco, California 94080 (US) JUDGE, Adam Daniel San Francisco, California 94080 (US) MANDEL, Alexander Laurence San Francisco, California 94080 (US) VISWAS, Raja Solomon San Francisco, California 94080 (US) MACKAY, Douglas Bruce Québec H4S1Z9 (CA) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)