(19)
(11) EP 4 577 642 A1

(12)

(43) Date of publication:
02.07.2025 Bulletin 2025/27

(21) Application number: 23768719.9

(22) Date of filing: 21.08.2023
(51) International Patent Classification (IPC): 
C12N 5/0793(2010.01)
(52) Cooperative Patent Classification (CPC):
C12N 5/062
(86) International application number:
PCT/US2023/030699
(87) International publication number:
WO 2024/044134 (29.02.2024 Gazette 2024/09)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 23.08.2022 US 202263373298 P
15.12.2022 US 202263432948 P

(71) Applicant: Astellas Institute for Regenerative Medicine
Westborough, MA 01581 (US)

(72) Inventors:
  • ABE, Masashi
    Westborough, MA 01581 (US)
  • DAO, Dang Quy
    Westborough, MA 01581 (US)
  • HILER, Daniel James
    Westborough, MA 01581 (US)
  • KIMBREL, Erin
    Westborough, MA 01581 (US)
  • LUO, Chenmei
    Westborough, MA 01581 (US)
  • PODOLSKIY, Dmitriy I.
    Westborough, MA 01581 (US)
  • REYES RAMIREZ, Santiago
    Westborough, MA 01581 (US)
  • THERIAULT, Kraig Marc
    Westborough, MA 01581 (US)
  • JO, Rebecca Eunkyung
    Westborough, MA 01581 (US)
  • PAULSEN, Samantha, Jean
    Westborough, MA 01581 (US)

(74) Representative: Hutter, Anton 
Venner Shipley LLP 5 Stirling House Stirling Road The Surrey Research Park
Guildford GU2 7RF
Guildford GU2 7RF (GB)

   


(54) PHOTORECEPTOR RESCUE CELL (PRC) COMPOSITIONS AND METHODS FOR TREATMENT OF OCULAR DISORDERS