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(11)

EP 4 580 588 A1

(12)

(43) Date of publication: 09.07.2025 Bulletin 2025/28 (21) Application number: 23859639.9 (22) Date of filing: 30.08.2023

(51) International Patent Classification (IPC):  A61K 8/14(2006.01) A61K 8/24(2006.01) A61K 47/69(2017.01) A61K 9/127(2025.01) A61K 9/06(2006.01) A61K 8/98(2006.01) A61K 47/24(2006.01) A61Q 19/00(2006.01) C07F 9/11(2006.01) C08F 10/00(2006.01) A61K 8/55(2006.01) A61K 8/02(2006.01) A61K 47/50(2017.01) A61K 47/30(2006.01) A61K 9/16(2006.01) A61K 31/66(2006.01) A61K 47/54(2017.01) C07F 9/10(2006.01) C08F 130/02(2006.01) A61P 17/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 8/14; A61K 8/55; A61P 17/00; A61Q 19/00; C08F 130/02; C08F 2438/00; A61K 2800/10; A61Q 5/02; A61Q 19/10; A61K 8/042; A61K 8/8152 (86) International application number: PCT/IL2023/050926 (87) International publication number: WO 2024/047646 (07.03.2024 Gazette 2024/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 30.08.2022 US 202263402088 P (71) Applicant: Liposphere Ltd. 5400804 Givat Shmuel (IL)	(72) Inventors: GOLDBERG, Ronit 5442802 Givat Shmuel (IL) JAHN, Sabrina High Pitfold Hindhead GU26 6BN (GB) LEVIN, Asaf 4942142 Petah Tikva (IL) (74) Representative: Mathys & Squire  The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)