(19)

(11)

EP 4 580 679 A1

(12)

(43) Date of publication: 09.07.2025 Bulletin 2025/28 (21) Application number: 23861512.4 (22) Date of filing: 30.08.2023

(51) International Patent Classification (IPC):  A61K 45/06(2006.01) A61K 31/27(2006.01) A61P 29/00(2006.01) C07D 405/04(2006.01) A61K 31/135(2006.01) A61P 25/00(2006.01) C07D 235/30(2006.01) C07D 471/04(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/27; A61K 45/06; A61P 25/00; A61P 29/00; A61K 31/167; A61K 31/472; A61K 31/4402; A61K 31/4439   C-Sets: A61K 31/27, A61K 2300/00; A61K 31/4439, A61K 2300/00; A61K 31/472, A61K 2300/00; A61K 31/4402, A61K 2300/00; A61K 31/167, A61K 2300/00; (86) International application number: PCT/US2023/073125 (87) International publication number: WO 2024/050389 (07.03.2024 Gazette 2024/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 30.08.2022 US 202263402416 P (71) Applicant: Biohaven Therapeutics Ltd. Tortola VG1110 (VG)	(72) Inventor: CORIC, Vladimir New Haven, Connecticut 06510 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)