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EP 4 581 013 A1

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(43) Date of publication: 09.07.2025 Bulletin 2025/28 (21) Application number: 23764241.8 (22) Date of filing: 23.08.2023

(51) International Patent Classification (IPC):  C07D 209/16(2006.01) A61P 25/28(2006.01) A61K 31/4045(2006.01) C07D 401/06(2006.01) A61P 25/24(2006.01) (52) Cooperative Patent Classification (CPC): C07D 209/16; C07D 401/06; A61P 25/28; A61P 25/24 (86) International application number: PCT/EP2023/073122 (87) International publication number: WO 2024/046837 (07.03.2024 Gazette 2024/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 31.08.2022 US 202263402650 P (71) Applicant: Cybin IRL Limited Dublin 1, D01X9R7 (IE)

(72) Inventors: NIVOROZHKIN, Alex West Roxbury, Massachusetts 02132 (US) HARTSEL, Joshua A. Lake Forest, California 92630 (US) CANAL, Clinton E. Atlanta, Georgia 30360 (US) MUELLER, Tina A. Palm Beach FL, Florida 33412 (US) AVERY, Kenneth L. Merrimack, New Hampshire 03054 (US) VARTY, Geoffrey B. Annandale, New Jersey 08801 (US) SALITURO, Francesco G. Marlborough, Massachusetts 01752-1374 (US) PALFREYMAN, Michael St. Petersburg, Florida 33701 (US) (74) Representative: Müller-Boré & Partner Patentanwälte PartG mbB  Friedenheimer Brücke 21 80639 München 80639 München (DE)