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EP 4 581 017 A1

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(43) Date of publication: 09.07.2025 Bulletin 2025/28 (21) Application number: 23789538.8 (22) Date of filing: 10.10.2023

(51) International Patent Classification (IPC):  C07D 215/40(2006.01) C07D 237/30(2006.01) C07D 401/12(2006.01) A61K 31/4709(2006.01) A61K 31/498(2006.01) C07D 217/02(2006.01) C07D 241/42(2006.01) A61P 29/00(2006.01) A61K 31/4725(2006.01) A61K 31/502(2006.01) (52) Cooperative Patent Classification (CPC): C07D 401/12; C07D 215/40; C07D 217/02; C07D 237/30; C07D 241/42; A61P 29/00 (86) International application number: PCT/EP2023/077957 (87) International publication number: WO 2024/079072 (18.04.2024 Gazette 2024/16)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 11.10.2022 EP 22306531 (71) Applicants: Biodol Therapeutics 34570 Montarnaud (FR) Institut National de la Santé et de la Recherche Médicale (INSERM) 75013 Paris (FR) Centre National de la Recherche Scientifique 75016 Paris (FR) UNIVERSITE DE MONTPELLIER 34090 Montpellier (FR) Université de Strasbourg 67000 Strasbourg (FR)

(72) Inventors: MORNAT, Pauline 67540 OSTWALD (FR) SOKOLOFF, Pierre 56780 ILE AUX MOINES (FR) ROGNAN, Didier 67210 BERNARDSWILLER (FR) (74) Representative: Ipsilon NNY  11 rue Saint-Georges 75009 Paris 75009 Paris (FR)