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(11)

EP 4 581 025 A1

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(43) Date of publication: 09.07.2025 Bulletin 2025/28 (21) Application number: 23776776.9 (22) Date of filing: 01.09.2023

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) A61K 31/45(2006.01) A61P 35/00(2006.01) A61K 31/506(2006.01) (52) Cooperative Patent Classification (CPC): C07D 401/14; A61P 35/00 (86) International application number: PCT/US2023/031835 (87) International publication number: WO 2024/050078 (07.03.2024 Gazette 2024/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 02.09.2022 US 202263403401 P 20.04.2023 US 202363460764 P (71) Applicant: Auron Therapeutics, Inc. Newton, Massachusetts 02458 (US)	(72) Inventors: NEEF, James Anthony Wellesley, Massachusetts 02481 (US) MILLAN, David Simon Wellesley, Massachusetts 02481 (US) MCRINER, Andrew John Wellesley, Massachusetts 02481 (US) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)