(19)
(11) EP 4 583 903 A1

(12)

(43) Date of publication:
16.07.2025 Bulletin 2025/29

(21) Application number: 23862612.1

(22) Date of filing: 06.09.2023
(51) International Patent Classification (IPC): 
A61K 38/48(2006.01)
A61P 27/02(2006.01)
C12N 9/64(2006.01)
 A61K 45/00(2006.01)
C07K 14/745(2006.01)
A61K 9/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 45/00; A61P 27/02; C07K 14/745; C12N 9/6464; C12Y 304/21069; A61P 27/00; A61P 29/00; A61K 9/0019; A61K 9/0051; A61K 38/4866
(86) International application number:
PCT/IB2023/058826
(87) International publication number:
WO 2024/052835 (14.03.2024 Gazette 2024/11)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(30) Priority: 06.09.2022 US 202263374651 P
25.05.2023 US 202363504288 P

(71) Applicants:
  • Livnat, Tami
    5252247 Ramat Gan (IL)
  • Weinberger, Dov
    5252247 Ramat Gan (IL)
  • Nisgav, Yael
    5252247 Ramat Gan (IL)
  • Griffin, John H.
    Del Mar, CA 92014 (US)
  • Mor Research Applications Ltd.
    5252247 Ramat Gan (IL)
  • The Scripps Research Institute
    La Jolla, CA 92037 (US)

(72) Inventors:
  • LIVNAT, Tami
    5252247 Ramat Gan (IL)
  • WEINBERGER, Dov
    5252247 Ramat Gan (IL)
  • NISGAV, Yael
    5252247 Ramat Gan (IL)
  • GRIFFIN, John H.
    Del Mar, California 92014 (US)

(74) Representative: Kasche & Partner 
Bühlstrasse 1
8125 Zollikerberg/Zürich
8125 Zollikerberg/Zürich (CH)

   


(54) METHODS OF TREATING INFLAMMATORY EYE DISEASES