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EP 4 583 910 A1

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(43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23776777.7 (22) Date of filing: 01.09.2023

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 7/02(2006.01) C07K 16/18(2006.01) A61P 7/00(2006.01) A61P 37/02(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/3955; A61P 7/00; A61P 7/02; A61P 37/02; C07K 16/18; A61K 2039/545; A61K 2039/55; A61K 2039/505; C07K 2317/76 (86) International application number: PCT/US2023/031836 (87) International publication number: WO 2024/054408 (14.03.2024 Gazette 2024/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 06.09.2022 US 202263404061 P 25.01.2023 US 202363440984 P (71) Applicant: Alexion Pharmaceuticals, Inc. Boston, MA 02210 (US)	(72) Inventors: ORTIZ, Stephan Boston, Massachusetts 02210 (US) MONTELEONE, Jonathan Boston, Massachusetts 02210 (US) REARS, Xiaofeng Wang Boston, Massachusetts 02210 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)