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EP 4 583 922 A2

(12)

(88) Date of publication A3: 11.04.2024 (43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23863945.4 (22) Date of filing: 06.09.2023

(51) International Patent Classification (IPC):  A61K 47/68(2017.01) A61K 47/64(2017.01) C07K 16/36(2006.01) A61K 47/54(2017.01) C07K 16/28(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 47/6849; A61K 47/6889; A61K 47/68037; C07K 16/36 (86) International application number: PCT/US2023/073516 (87) International publication number: WO 2024/054821 (14.03.2024 Gazette 2024/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 07.09.2022 US 202263404447 P 25.04.2023 US 202363498233 P (71) Applicant: Exelixis, Inc. Alameda, CA 94502 (US)	(72) Inventors: BARFIELD, Robyn, M. Alameda, CA 94502 (US) BAUZON, Maxine Alameda, CA 94502 (US) DRAKE, Penelope, M. Alameda, CA 94502 (US) KANTAK, Seema Alameda, CA 94502 (US) MENDELSOHN, Brian, Alan Alameda, CA 94502 (US) UNSULANGI, Tiffany Alameda, CA 94502 (US) (74) Representative: Jones Day  Rechtsanwälte, Attorneys-at-Law, Patentanwälte Gewürzmühlstraße 11 80538 München 80538 München (DE)