(19)

(11)

EP 4 584 250 A1

(12)

(43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23863939.7 (22) Date of filing: 06.09.2023

(51) International Patent Classification (IPC):  C07D 235/30(2006.01) A61P 25/24(2006.01) A61K 31/4168(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/24; A61K 45/06   C-Sets: A61K 31/47, A61K 2300/00; A61K 31/27, A61K 2300/00; A61K 31/428, A61K 2300/00; A61K 31/4184, A61K 2300/00; (86) International application number: PCT/US2023/073504 (87) International publication number: WO 2024/054811 (14.03.2024 Gazette 2024/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 06.09.2022 US 202263403911 P (71) Applicant: Biohaven Therapeutics Ltd. Tortola VG1110 (VG)	(72) Inventors: CORIC, Vladimir New Haven, CT 06510 (US) DWORETZKY, Steven I. New Haven, CT 06510 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)