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(11)

EP 4 584 255 A1

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(43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23862542.0 (22) Date of filing: 11.09.2023

(51) International Patent Classification (IPC):  C07D 401/06(2006.01) A61P 27/00(2006.01) A61K 31/454(2006.01) (52) Cooperative Patent Classification (CPC): C07D 401/06; A61P 27/00; C07D 491/107; C07D 471/10 (86) International application number: PCT/CN2023/117941 (87) International publication number: WO 2024/051849 (14.03.2024 Gazette 2024/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 10.09.2022 US 202263375224 P (71) Applicants: Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Lianyungang, Jiangsu 222047 (CN) Hansoh Bio LLC Rockville, Maryland 20850 (US) Shanghai Hansoh Biomedical Co., Ltd. Shanghai 201203 (CN)

(72) Inventors: KHANNA, Avinash Rockville, Maryland 20850 (US) KIER, Matthew Rockville, Maryland 20850 (US) ZHU, Hugh Y. Rockville, Maryland 20850 (US) (74) Representative: Murgitroyd & Company  165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)