(19)

(11)

EP 4 584 286 A1

(12)

(43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23768282.8 (22) Date of filing: 08.09.2023

(51) International Patent Classification (IPC):  C07K 14/705(2006.01) A61P 35/00(2006.01) A61K 38/00(2006.01) C12N 9/10(2006.01) (52) Cooperative Patent Classification (CPC): A61K 38/00; C07K 2319/00; C07K 14/705; C12N 9/10; A61P 35/00 (86) International application number: PCT/EP2023/074709 (87) International publication number: WO 2024/052522 (14.03.2024 Gazette 2024/11)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 09.09.2022 EP 22194882 (71) Applicant: Deutsches Krebsforschungszentrum 69120 Heidelberg (DE)	(72) Inventors: NIEHRS, Christof 69120 Heidelberg (DE) SUN, Rui 69120 Heidelberg (DE) (74) Representative: Altmann Stößel Dick Patentanwälte PartG mbB  Theodor-Heuss-Anlage 2 68165 Mannheim 68165 Mannheim (DE)