(19)

(11)

EP 4 584 299 A2

(12)

(88) Date of publication A3: 16.01.2025 (43) Date of publication: 16.07.2025 Bulletin 2025/29 (21) Application number: 23928994.5 (22) Date of filing: 03.09.2023

(51) International Patent Classification (IPC):  C07K 16/44(2006.01) A61P 25/36(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/70; C07K 16/44; C07K 2317/22; C07K 2317/569; C07K 2317/92; A61P 25/36 (86) International application number: PCT/US2023/031942 (87) International publication number: WO 2024/228717 (07.11.2024 Gazette 2024/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (30) Priority: 07.09.2022 US 202263404495 P (71) Applicant: Quantitative Biosciences, Inc. San Diego, CA 92121 (US)	(72) Inventors: CSICSERY, Nicholas, Sigmund San Diego, CA 92131 (US) FERRY, Michael, Stephen San Diego, CA 92127 (US) COOKSON, Scott, Warren Encinitas, CA 92024 (US) COOKSON, Natalie, Anne Encinitas, CA 92024 (US) MATHER, William, H. Encinitas, CA 92024 (US) (74) Representative: Latscha Schöllhorn Partner AG  Grellingerstrasse 60 4052 Basel 4052 Basel (CH)