(19)

(11)

EP 4 680 220 A1

(12)

(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24710797.2 (22) Date of filing: 15.03.2024

(51) International Patent Classification (IPC):  A61K 31/18(2006.01) A61K 31/4418(2006.01) A61K 31/10(2006.01) A61P 19/00(2006.01) A61P 29/00(2006.01) A61P 37/00(2006.01) A61K 31/277(2006.01) A61K 31/445(2006.01) A61P 11/00(2006.01) A61P 19/02(2006.01) A61P 35/00(2006.01) A61P 43/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/18; A61K 31/277; A61K 31/4418; A61K 31/445; A61K 31/10; A61P 11/00; A61P 19/00; A61P 19/02; A61P 29/00; A61P 35/00; A61P 37/00; A61P 43/00 (86) International application number: PCT/EP2024/057086 (87) International publication number: WO 2024/189230 (19.09.2024 Gazette 2024/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.03.2023 EP 23162131 (71) Applicant: Istesso 1 Limited London N1C 4AG (GB)	(72) Inventors: FOSTER, Martyn Leslie Benfleet Essex SS7 5JQ (GB) MAZANETZ, Michael Philip Glasgow G43 2NX (GB) PATEL, Lisa London N1C 4AG (GB) VINK, Paul Nijmegen (NL) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)