(19)
(11) EP 4 680 261 A1

(12)

(43) Date of publication:
21.01.2026 Bulletin 2026/04

(21) Application number: 23927883.1

(22) Date of filing: 17.03.2023
(51) International Patent Classification (IPC): 
A61K 38/06(2006.01)
A61K 35/74(2015.01)
 A61K 38/00(2006.01)
(52) Cooperative Patent Classification (CPC):
Y02A 50/30; A61K 38/06; A61K 35/741
 
C-Sets:
  1. A61K 38/06, A61K 2300/00;
  2. A61K 35/741, A61K 2300/00;
(86) International application number:
PCT/CN2023/082184
(87) International publication number:
WO 2024/192564 (26.09.2024 Gazette 2024/39)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(71) Applicants:
  • The Regents Of The University Of Michigan
    Ann Arbor, Michigan 48109 (US)
  • Peking University Health Science Center
    Beijing 100191 (CN)

(72) Inventors:
  • CHEN, Yuqing Eugene
    Ann Arbor, Michigan 48109-2800 (US)
  • ZHANG, Jifeng
    Ann Arbor, Michigan 48109-2800 (US)
  • ZHENG, Lemin
    Beijing 100191 (CN)

(74) Representative: Algemeen Octrooi- en Merkenbureau B.V. 
P.O. Box 645
5600 AP Eindhoven
5600 AP Eindhoven (NL)

   


(54) PRODUCTS AND METHODS FOR TREATING METABOLIC, CARDIOVASCULAR, INFLAMMATORY AND ONCOLOGICAL DISEASES