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EP 4 680 273 A1

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(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24771805.9 (22) Date of filing: 15.03.2024

(51) International Patent Classification (IPC):  A61K 39/112(2006.01) A61K 47/54(2017.01) A61P 31/00(2006.01) C07K 19/00(2006.01) A61K 39/39(2006.01) A61K 47/66(2017.01) A61K 39/09(2006.01) (52) Cooperative Patent Classification (CPC): A61P 31/00; C07K 19/00; A61K 39/092; A61K 2039/55505; A61K 2039/575; A61K 2039/625; A61K 2039/645; A61K 2039/6068; A61K 47/646 (86) International application number: PCT/US2024/020141 (87) International publication number: WO 2024/192346 (19.09.2024 Gazette 2024/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 16.03.2023 US 202363452681 P (71) Applicant: Affinivax, Inc. Wilmington, DE 19808 (US)	(72) Inventors: LOUN, Bounthon Cambridge, Massachusetts 02142 (US) STEVENSON, Taylor C. Cambridge, Massachusetts 02142 (US) (74) Representative: West, Heloise  GSK Legal & Compliance - Global Patents 79 New Oxford Street London WC1A 1DG London WC1A 1DG (GB)