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(11)

EP 4 680 279 A1

(12)

(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24718949.1 (22) Date of filing: 12.03.2024

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/28(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2803; C07K 16/2818; C07K 16/2809; C07K 16/2887; A61K 39/395; A61P 35/00; A61K 2039/505; A61K 2039/545; C07K 2317/31   C-Sets: A61K 39/395, A61K 2300/00; (86) International application number: PCT/US2024/019506 (87) International publication number: WO 2024/191983 (19.09.2024 Gazette 2024/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.03.2023 US 202363489808 P (71) Applicant: Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591-6706 (US)	(72) Inventors: CHAUDHRY, Aafia Tarrytown, NY 10591 (US) MOHAMED, Hesham Tarrytown, NY 10591 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)