(19)

(11)

EP 4 680 288 A1

(12)

(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24720358.1 (22) Date of filing: 16.03.2024

(51) International Patent Classification (IPC):  A61K 49/00(2006.01) A61K 39/395(2006.01) C07K 16/18(2006.01) A61P 25/28(2006.01) (52) Cooperative Patent Classification (CPC): A61K 49/0008; C07K 16/18; A61P 25/28; A01K 2207/15; A01K 2217/052; A01K 2267/0312; A01K 2207/10; G01N 33/6896; A61K 2039/505 (86) International application number: PCT/US2024/020329 (87) International publication number: WO 2024/192429 (19.09.2024 Gazette 2024/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 16.03.2023 US 202363490715 P (71) Applicant: Abbvie Inc. North Chicago, Illinois 60064 (US)	(72) Inventor: SMITH, Tammy, D. Carlisle, Massachusetts 01741 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)