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EP 4 680 631 A1

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(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24707819.9 (22) Date of filing: 01.03.2024

(51) International Patent Classification (IPC):  C07K 16/00(2006.01) C07K 16/30(2006.01) C07K 16/28(2006.01) C12N 15/10(2006.01) (52) Cooperative Patent Classification (CPC): C07K 2317/622; C07K 2317/31; C07K 2317/92; C07K 16/005; C07K 16/2896; C07K 16/3092; C07K 2317/24; C07K 2317/56; C07K 2317/34; C07K 2317/565; C12N 15/1037 (86) International application number: PCT/EP2024/055483 (87) International publication number: WO 2024/193989 (26.09.2024 Gazette 2024/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 17.03.2023 WO PCT/EP2023/056922 01.12.2023 US 202318526205 (71) Applicants: Danmarks Tekniske Universitet 2800 Kongens Lyngby (DK) Universidad De Zaragoza 50009 Zaragoza (ES) Fundación Agencia Aragonesa para la Investigación y el Desarrollo (ARAID) 50018 Zaragoza (ES)

(72) Inventors: BLIXT, Ola 2800 Kongens Lyngby (DK) HURTADO GUERRERO, Ramón 50018 Zaragova (ES) GATOS, Spyridon 2800 Kongens Lyngby (DK) (74) Representative: Guardian IP Consulting I/S  Diplomvej, Building 381 2800 Kgs. Lyngby 2800 Kgs. Lyngby (DK)