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(11)

EP 4 680 645 A1

(12)

(43) Date of publication: 21.01.2026 Bulletin 2026/04 (21) Application number: 24775470.8 (22) Date of filing: 15.03.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) C07K 14/54(2006.01) A61P 35/00(2006.01) C07K 19/00(2006.01) A61K 47/68(2017.01) A61K 38/20(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/2863; C07K 2317/33; C07K 2317/622; C07K 2317/92; C07K 16/005; C07K 2317/21; C07K 2317/24; C07K 2317/524; C07K 2317/526; C07K 2317/71; C07K 2317/52; C07K 16/46; C07K 2317/76; A61K 40/11; A61K 40/31; A61K 40/4211; A61K 2039/505; C07K 14/55; C07K 2317/35; C07K 2319/00; C07K 14/71; A61K 38/00   C-Sets: A61K 40/11, A61K 2300/00; (86) International application number: PCT/US2024/020263 (87) International publication number: WO 2024/196798 (26.09.2024 Gazette 2024/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 17.03.2023 US 202363490966 P (71) Applicant: Asher Biotherapeutics, Inc. South San Francisco, CA 94080 (US)	(72) Inventors: YEUNG, Yik Andy San Francisco, California 94080 (US) BESSETTE, Paul San Francisco, California 94080 (US) MATHEWSON, Nathan San Francisco, California 94080 (US) MATSUMOTO, Marissa San Francisco, California 94080 (US) DJURETIC, Ivana San Francisco, California 94080 (US) (74) Representative: Murgitroyd & Company  165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)