(19)
(11) EP 4 681 205 A2

(12)

(88) Date of publication A3:
04.09.2025

(43) Date of publication:
21.01.2026 Bulletin 2026/04

(21) Application number: 24771602.0

(22) Date of filing: 12.03.2024
(51) International Patent Classification (IPC): 
G16B 20/20(2019.01)
C12Q 1/6886(2018.01)
 C12Q 1/6827(2018.01)
(52) Cooperative Patent Classification (CPC):
C12Q 1/6886; G16B 20/20; C12Q 2600/156; G16H 20/10; G16B 20/10
(86) International application number:
PCT/US2024/019597
(87) International publication number:
WO 2024/192044 (19.09.2024 Gazette 2024/38)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 16.03.2023 US 202363452570 P
06.06.2023 US 202363506473 P

(71) Applicant: Roswell Park Cancer Institute Corporation
Buffalo, New York 14263 (US)

(72) Inventors:
  • GLYNIAS, Manuel
    Buffalo, NY 14263 (US)
  • MORRISON, Carl
    Buffalo, NY 14263 (US)
  • GLENN, Sean
    Buffalo, NY 14263 (US)

(74) Representative: Grünecker Patent- und Rechtsanwälte PartG mbB 
Leopoldstraße 4
80802 München
80802 München (DE)

   


(54) SYSTEMS AND METHODS FOR DETECTING HEMATOPOIETIC NEOPLASMS USING DEOXYRIBONUCLEIC ACID (DNA) MUTATIONS