(19)
(11) EP 4 681 206 A1

(12)

(43) Date of publication:
21.01.2026 Bulletin 2026/04

(21) Application number: 24714826.5

(22) Date of filing: 15.03.2024
(51) International Patent Classification (IPC): 
G16B 20/30(2019.01)
G16B 30/00(2019.01)
G16B 20/50(2019.01)
(52) Cooperative Patent Classification (CPC):
G16B 20/30; G16B 20/50; G16B 30/00
(86) International application number:
PCT/EP2024/057045
(87) International publication number:
WO 2024/194207 (26.09.2024 Gazette 2024/39)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 17.03.2023 GB 202303934

(71) Applicant: Thermo Fisher Scientific GENEART GmbH
93059 Regensburg (DE)

(72) Inventors:
  • HOFMEISTER, Thomas
    93059 Regensburg (DE)
  • LISS, Michael
    93059 Regensburg (DE)

(74) Representative: Grund, Martin et al
Grund Intellectual Property Group Patentanwälte und Solicitor PartG mbB Steinsdorfstraße 2
80538 München
80538 München (DE)

   


(54) METHODS OF PRODUCING MODIFIED NUCLEIC ACID SEQUENCES FOR ELIMINATING ADVERSE SPLICING EVENTS