A system for aerial neutralization of a detected target aerial vehicle comprises a plurality of counter-attack unmanned aerial vehicles (UAVs), and an aerial vehicle capture countermeasure coupling together the plurality of counter-attack UAVs, to intercept and capture a detected target aerial vehicle in a coordinated manner. The system comprises an aerial vehicle detection system comprising at least one detection sensor operable to detect the target aerial vehicle, and operable to provide command data to at least one counter-attack UAV for tracking and neutralizing the target aerial vehicle. The counter-attack UAVs and a net can be deployed from a movable base station, and the net can be carried in a low-drag configuration until the counter-attack UAVs operate to deploy or open the net. The counter-attack UAVs and systems may be autonomously operated. Associated systems and methods are provided.