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EP 4 739 283 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24742694.3 (22) Date of filing: 03.07.2024

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 38/01(2006.01) A61K 47/34(2017.01) A61P 5/50(2006.01) A61K 9/51(2006.01) A61K 38/28(2006.01) A61K 47/59(2017.01) (52) Cooperative Patent Classification (CPC): A61K 38/28; A61K 47/34; A61K 9/0024; A61K 9/5153; A61P 5/50; A61K 38/09; A61K 38/31 (86) International application number: PCT/IL2024/050649 (87) International publication number: WO 2025/008819 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 05.07.2023 US 202363511962 P (71) Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. 9139002 Jerusalem (IL)	(72) Inventor: DOMB, Abraham Yaacov 9359006 Jerusalem (IL) (74) Representative: Weickmann & Weickmann PartmbB  Postfach 860 820 81635 München 81635 München (DE)