(19)
(11) EP 4 739 320 A1

(12)

(43) Date of publication:
13.05.2026 Bulletin 2026/20

(21) Application number: 24852486.0

(22) Date of filing: 06.08.2024
(51) International Patent Classification (IPC): 
A61K 33/22(2006.01)
A61P 35/00(2006.01)
 A61K 31/593(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 33/22; A61P 35/00; A61K 31/593
 
C-Sets:
  1. A61K 31/593, A61K 2300/00;
  2. A61K 33/22, A61K 2300/00;
(86) International application number:
PCT/TR2024/050920
(87) International publication number:
WO 2025/034188 (13.02.2025 Gazette 2025/07)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 07.08.2023 TR 2023009397

(71) Applicant: Yeditepe Universitesi
34755 Atasehir/Istanbul (TR)

(72) Inventors:
  • SAHIN, Fikrettin
    34755 Atasehir/Istanbul (TR)
  • OMEROGLU ULU, Zehra
    34755 Atasehir/Istanbul (TR)
  • DEGIRMENCI, Nurdan Sena
    34755 Atasehir/Istanbul (TR)
  • PADAR, Gamze
    34755 Atasehir/Istanbul (TR)

(74) Representative: Yalçiner Patent and Consulting Ltd. 
Tunus Caddesi 85/3-4 Kavaklidere
06680 Ankara
06680 Ankara (TR)

   


(54) ANTI-CANCER EFFECT OF THE COMBINATION OF SODIUM PENTABORATE PENTAHIDRATE AND VITAMIN D ACTIVE FORM CALCITRIOL AGAINST HEPATOCELLULAR CARCINOMA