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EP 4 739 341 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24740407.2 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) C12N 15/113(2010.01) (52) Cooperative Patent Classification (CPC): A61K 2239/48; C12N 15/1138; C12N 2310/20; A61K 40/15; A61K 40/4224; A61K 40/50; A61K 40/31 (86) International application number: PCT/EP2024/069002 (87) International publication number: WO 2025/008507 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 06.07.2023 EP 23183973 (71) Applicant: Universitätsklinikum Hamburg-Eppendorf 20246 Hamburg (DE)	(72) Inventors: AYUK, Ayuketang Francis 20246 Hamburg (DE) FEHSE, Boris 20246 Hamburg (DE) HARFMANN, Maraike 22307 Hamburg (DE) GLOW, Dawid 20246 Hamburg (DE) SCHROEDER, Tanja 20246 Hamburg (DE) (74) Representative: Eisenführ Speiser  Patentanwälte Rechtsanwälte PartGmbB Johannes-Brahms-Platz 1 20355 Hamburg 20355 Hamburg (DE)