(19)

(11)

EP 4 739 350 A1

(12)

(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24746571.9 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  A61K 48/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 48/0075; C12N 15/86; A61K 9/0048; A61K 9/0019; A61K 48/005 (86) International application number: PCT/US2024/036954 (87) International publication number: WO 2025/014832 (16.01.2025 Gazette 2025/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 07.07.2023 US 202363512546 P 29.12.2023 US 202363616045 P (71) Applicant: Kriya Therapeutics, Inc. Morrisville, NC 27560 (US)

(72) Inventors: STONE, Michele Morrisville, NC 27560 (US) CEPEDA, Diana Morrisville, NC 27560 (US) CASTELLANOS, Ruth Morrisville, NC 27560 (US) ENGLES, Michael Morrisville, NC 27560 (US) RAMASWAMY, Shankar Morrisville, NC 27560 (US) MURPHY, Andrew Morrisville, NC 27560 (US) ECLOV, Rachel Morrisville, NC 27560 (US) (74) Representative: EIP  Fairfax House 15 Fulwood Place London WC1V 6HU London WC1V 6HU (GB)