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EP 4 739 363 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 23944448.2 (22) Date of filing: 05.07.2023

(51) International Patent Classification (IPC):  A61L 31/10(2006.01) A61L 31/16(2006.01) A61L 31/02(2006.01) (52) Cooperative Patent Classification (CPC): A61L 31/10; A61L 31/16; A61L 31/022; A61L 2300/25; A61L 31/047   C-Sets: A61L 31/10, C08L 89/00; (86) International application number: PCT/KR2023/009465 (87) International publication number: WO 2025/009632 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (71) Applicants: Industry Foundation of Chonnam National University Gwangju 61186 (KR) Chonnam National University Hospital Gwangju 61469 (KR) CG Bio Co., Ltd. Seoul 04349 (KR) Universidade Da Coruña 15001 A Coruña (ES) Fundación Pública Galega de Investigación Biomédica INIBIC 15006 A Coruña (ES) Servizo Galego de Saúde (SERGAS) 15703 Santiago de Composteia (ES) Gutiérrez-Chico, Juan Luis 56068 Koblenz (DE)

(72) Inventors: JEONG, Myung Ho Gwangju 61708 (KR) SIM, Doo Sun Gwangju 61957 (KR) KEE, Seung Jung Gwangju 61706 (KR) AHN, Youngkeun Gwangju 61707 (KR) KIM, Ju Han Gwangju 61412 (KR) HONG, Young Joon Gwangju 61706 (KR) PARK, Dae Sung Gwangju 61446 (KR) KIM, Mun Ki Gwangju 61019 (KR) CHO, Young-Nan Hwasun-gun Jeollanam-do 58137 (KR) CHO, Kyung Hoon Gwangju 61736 (KR) HYUN, Dae Young Gwangju 61729 (KR) JIN, Yu Jeong Gwangju 62279 (KR) OH, Seok Gwangju 61697 (KR) NA, Mi Hyang Gwangju 62279 (KR) KIM, Taehun Hanam-si Gyeonggi-do 13012 (KR) BYEON, Daeheung Gwangju 61015 (KR) HERMIDA-PRIETO, Manuel 15001 A Coruña A Coruña (ES) MARIÑAS PARDO, Luis 15006 A Coruña A Coruña (ES) VAZQUEZ RODRIGUEZ, Jose Manuel 15001 A Coruña A Coruña (ES) GUTIÉRREZ-CHICO, Juan Luis 56068 Koblenz (DE) (74) Representative: Hoffmann Eitle  Hoffmann Eitle S.L.U. Paseo de la Castellana 140, 3a planta Edificio LIMA 28046 Madrid 28046 Madrid (ES)