(19)

(11)

EP 4 739 366 A2

(12)

(88) Date of publication A3: 08.05.2025 (43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24840390.9 (22) Date of filing: 08.07.2024

(51) International Patent Classification (IPC):  A61M 1/00(2006.01) A61J 15/00(2006.01) A61N 1/05(2006.01) A61M 39/10(2006.01) (52) Cooperative Patent Classification (CPC): A61M 16/0463; A61M 2205/7536; A61M 2230/65; A61M 2230/60; A61M 2205/0266; A61M 2205/0205; G16H 20/40; A61M 2205/505; A61M 2205/82; A61M 2209/10; A61N 1/0517; A61N 1/0519; A61N 1/3606; A61M 1/87; A61M 27/00; A61M 25/0045; G16H 40/63   C-Sets: A61M 2230/65, A61M 2230/005; A61M 2230/60, A61M 2230/005; (86) International application number: PCT/US2024/037086 (87) International publication number: WO 2025/014894 (16.01.2025 Gazette 2025/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 07.07.2023 US 202363512358 P 30.04.2024 US 202463640342 P (71) Applicant: Yale University New Haven CT 06510 (US)	(72) Inventors: BONDE, Pramod New Haven, CT 06511 (US) GUPTA, Rigu New Haven, CT 06511 (US) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)