(19)

(11)

EP 4 739 395 A2

(12)

(88) Date of publication A3: 06.03.2025 (43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24743467.3 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07K 16/28(2006.01) C07K 14/725(2006.01) C07K 16/30(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/30; C07K 16/2809; C07K 2317/31; C07K 2317/53; C07K 2317/94; C07K 2319/00; C07K 2317/622; C07K 2317/624; C07K 16/2833; A61P 35/00 (86) International application number: PCT/GB2024/051771 (87) International publication number: WO 2025/008643 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 05.07.2023 US 202363512019 P (71) Applicant: Enara Bio Limited Oxford, OX4 4GA (GB)	(72) Inventors: VON ESSEN, Magdalena Oxford OX4 4GA (GB) HOWIE, Duncan Oxford OX4 4GA (GB) MASON, Peter New Castle, Delaware 19801 (US) LAM, Emily Oxford OX4 4GA (GB) CORNFORTH, Terri Oxford OX4 4GA (GB) (74) Representative: Sagittarius IP  Marlow International Parkway Marlow SL7 1YL Marlow SL7 1YL (GB)