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EP 4 739 397 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24748732.5 (22) Date of filing: 02.07.2024

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07D 471/08(2006.01) C07D 471/18(2006.01) C07D 498/04(2006.01) A61K 31/506(2006.01) A61K 31/553(2006.01) A61K 31/5365(2006.01) A61K 31/5386(2006.01) C07D 471/04(2006.01) C07D 471/10(2006.01) C07D 487/04(2006.01) C07D 498/18(2006.01) A61K 31/551(2006.01) A61K 31/519(2006.01) A61K 31/5517(2006.01) A61K 31/55(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/08; C07D 471/04; C07D 471/10; C07D 471/18; C07D 487/04; C07D 498/18; C07D 498/04; A61P 35/00 (86) International application number: PCT/US2024/036492 (87) International publication number: WO 2025/010245 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 06.07.2023 IN 202341045361 (71) Applicant: Exelixis, Inc. Alameda, CA 94502 (US)	(72) Inventors: ABBINENI, Chandrasekhar Hyderabad Telangana 500 072 (IN) SAMAJDAR, Susanta Bangalore Karnataka 560078 (IN) AELURI, Madhu Bangalore Karnataka 560078 (IN) SIMONOVICH, Scott Oakland, California 94602 (US) (74) Representative: Mathys & Squire  32 London Bridge Street The Shard London SE1 9SG London SE1 9SG (GB)