(19)

(11)

EP 4 739 663 A1

(12)

(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24740411.4 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  C07D 295/125(2006.01) A61K 47/69(2017.01) (52) Cooperative Patent Classification (CPC): C07D 295/125; A61K 9/5123 (86) International application number: PCT/EP2024/069013 (87) International publication number: WO 2025/008510 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 06.07.2023 EP 23183820 (71) Applicant: eTheRNA immunotherapies NV 2845 Niel (BE)	(72) Inventors: KASMI, Sabah 2845 Niel (BE) DE COEN, Ruben 2845 Niel (BE) DE KOKER, Stefaan 2845 Niel (BE) DUMBRE, Shrinivas 2845 Niel (BE) (74) Representative: Arnold & Siedsma  Bezuidenhoutseweg 57 2594 AC The Hague 2594 AC The Hague (NL)