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(11)

EP 4 739 667 A2

(12)

(88) Date of publication A3: 13.02.2025 (43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24740851.1 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  C07D 401/04(2006.01) C07D 403/14(2006.01) A61P 13/12(2006.01) A61P 27/00(2006.01) A61K 31/403(2006.01) C07D 401/14(2006.01) C07D 491/02(2006.01) A61P 25/28(2006.01) A61P 37/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 403/14; C07D 401/04; C07D 401/14; C07D 491/02; A61P 25/28; A61P 37/00; A61P 13/12; A61P 27/00 (86) International application number: PCT/EP2024/069024 (87) International publication number: WO 2025/008516 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 06.07.2023 GB 202310422 06.11.2023 GB 202316974 (71) Applicant: Sitala Bio Ltd Great Shelford Cambridge CB22 5LD (GB)	(72) Inventors: CHRISTOPHER, John Andrew Cambridge CB22 5LD (GB) WYATT, Paul Graham Cambridge CB22 5LD (GB) HORNSBY, Thomas William Nottingham NG1 1GR (GB) COOPER, Martin Edward Nottingham NG1 1GR (GB) MILLS, Mark Nottingham NG1 1GR (GB) (74) Representative: Johnson, Stephen William et al Venner Shipley LLP 406 Cambridge Science Park Milton Road Cambridge CB4 0WW Cambridge CB4 0WW (GB)