(19)
(11) EP 4 739 670 A1

(12)

(43) Date of publication:
13.05.2026 Bulletin 2026/20

(21) Application number: 24740377.7

(22) Date of filing: 04.07.2024
(51) International Patent Classification (IPC): 
C07D 401/12(2006.01)
C07D 405/14(2006.01)
C07D 413/14(2006.01)
C07B 59/00(2006.01)
A61K 31/4162(2006.01)
 C07D 401/14(2006.01)
C07D 413/06(2006.01)
C07D 487/04(2006.01)
A61P 37/02(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 37/02; C07D 487/04; C07D 413/14; C07D 413/06; C07D 401/12; C07D 401/14; C07D 405/14; C07B 59/002; C07B 2200/05
(86) International application number:
PCT/EP2024/068795
(87) International publication number:
WO 2025/012057 (16.01.2025 Gazette 2025/03)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 07.07.2023 WO PCT/CN2023/106401

(71) Applicant: F. Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • JIANG, Min
    Shanghai 201203 (CN)
  • KOU, Buyu
    Shanghai 201203 (CN)
  • LIU, Haixia
    Shanghai 201203 (CN)
  • SHEN, Hong
    Shanghai 201203 (CN)
  • WU, Yao
    Shanghai 201203 (CN)
  • ZHANG, Zhiwei
    Shanghai 201203 (CN)
  • ZHU, Wei
    Shanghai 201203 (CN)

(74) Representative: Bernard, Guillaume 
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)

   


(54) MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE