(19)

(11)

EP 4 739 672 A1

(12)

(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24742991.3 (22) Date of filing: 03.07.2024

(51) International Patent Classification (IPC):  C07D 401/12(2006.01) A61K 31/495(2006.01) A61P 25/28(2006.01) (52) Cooperative Patent Classification (CPC): C07D 401/12; A61P 25/28; A61K 31/496; A61K 31/47 (86) International application number: PCT/GB2024/051729 (87) International publication number: WO 2025/008626 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 04.07.2023 GB 202310233 (71) Applicant: Aston University Birmingham West Midlands B4 7ET (GB)	(72) Inventors: GRIFFIN, Martin Birmingham West Midlands B4 7ET (GB) WANG, Zhuo Birmingham West Midlands B4 7ET (GB) RATHBONE, Daniel L Birmingham West Midlands B4 7ET (GB) AQIL, Rehan Walden Essex CB10 1XL (GB) RATCLIFFE, Andrew James Walden Essex CB10 1XL (GB) (74) Representative: Potter Clarkson  Chapel Quarter Mount Street Nottingham NG1 6HQ Nottingham NG1 6HQ (GB)