(19)
(11) EP 4 739 675 A1

(12)

(43) Date of publication:
13.05.2026 Bulletin 2026/20

(21) Application number: 24740852.9

(22) Date of filing: 05.07.2024
(51) International Patent Classification (IPC): 
C07D 401/14(2006.01)
A61P 37/00(2006.01)
A61P 27/00(2006.01)
A61K 31/415(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 401/14; A61P 27/00; A61P 37/00
(86) International application number:
PCT/EP2024/069027
(87) International publication number:
WO 2025/008517 (09.01.2025 Gazette 2025/02)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 06.07.2023 GB 202310423
06.11.2023 GB 202316975

(71) Applicant: Sitala Bio Ltd
Great Shelford Cambridge CB22 5LD (GB)

(72) Inventors:
  • CHRISTOPHER, John Andrew
    Cambridge CB22 5LD (GB)
  • WYATT, Paul Graham
    Cambridge CB22 5LD (GB)
  • HORNSBY, Thomas William
    Nottingham NG1 1GR (GB)
  • MILLS, Mark
    Nottingham NG1 1GR (GB)

(74) Representative: Johnson, Stephen William et al
Venner Shipley LLP 406 Cambridge Science Park Milton Road
Cambridge CB4 0WW
Cambridge CB4 0WW (GB)

   


(54) INDOLE DERIVATIVES WITH FACTOR B INHIBITORY ACTIVITY