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EP 4 739 682 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 23741601.1 (22) Date of filing: 05.07.2023

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61K 31/4375(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04; A61K 31/4375; A61P 35/00 (86) International application number: PCT/EP2023/068560 (87) International publication number: WO 2025/008058 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: KH MA MD TN (71) Applicant: Janssen Pharmaceutica NV 2340 Beerse (BE)

(72) Inventors: STANSFIELD, Ian 2340 Beerse (BE) MEVELLEC, Laurence, Anne 92787 Issy-les Moulineaux Cedex 9 (FR) PANDE, Vineet 2340 Beerse (BE) DE BOECK, Benoît Christian Albert Ghislain 2340 Beerse (BE) BRAMBILLA, Marta 2340 Beerse (BE) JONES, Alexander Xenophon 2340 Beerse (BE) ALCÁZAR VACA, Manuel Jesús 28042 Madrid (ES) JONES, William Moore Raritan, New Jersey 08869 (US) SHIMKIN, Kirk Wayne Raritan, New Jersey 08869 (US) CALLAS, Christopher George Raritan, New Jersey 08869 (US) WINTERS, Michael Peter Raritan, New Jersey 08869 (US) ROSANO, Robert J Raritan, New Jersey 08869 (US) KRAWCZUK, Paul John Titusville, NJ 08560 USA (US) BERTHELOT, Didier Jean Claude 2340 Beerse (BE) (74) Representative: Campabadal Monfa, Gemma  Johnson & Johnson Patent Law Department Turnhoutseweg 30 2340 Beerse 2340 Beerse (BE)