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EP 4 739 686 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24740378.5 (22) Date of filing: 04.07.2024

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61K 31/4375(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 471/04; A61P 35/00 (86) International application number: PCT/EP2024/068799 (87) International publication number: WO 2025/008436 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 05.07.2023 US 202363511907 P (71) Applicant: Janssen Pharmaceutica NV 2340 Beerse (BE)

(72) Inventors: STANSFIELD, Ian 2340 Beerse (BE) KRAWCZUK, Paul John Titusville, NJ 08560 (US) WINTERS, Michael Peter Raritan, NJ 08869 (US) SHIMKIN, Kirk Wayne Raritan, NJ 08869 (US) ALCÁZAR VACA, Manuel Jesús 28042 Madrid (ES) BRAMBILLA, Marta 2340 Beerse (BE) PANDE, Vineet 2340 Beerse (BE) MEVELLEC, Laurence Anne 92787 Issy-les-Moulineaux Cedex 9 (FR) DE BOECK, Benoît Christian Albert Ghislain 2340 Beerse (BE) JONES, Alexander Xenophon 2340 Beerse (BE) JONES, William Moore Raritan, NJ 08869 (US) CALLAS, Christopher George Raritan, NJ 08869 (US) ROSANO, Robert J Raritan, NJ 08869 (US) (74) Representative: Campabadal Monfa, Gemma  Johnson & Johnson Patent Law Department Turnhoutseweg 30 2340 Beerse 2340 Beerse (BE)