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(11)

EP 4 739 705 A1

(12)

(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24840338.8 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61P 25/28(2006.01) A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/18; A61P 25/28; A61K 2039/505; C07K 2317/77 (86) International application number: PCT/US2024/036930 (87) International publication number: WO 2025/014821 (16.01.2025 Gazette 2025/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 07.07.2023 US 202363512412 P (71) Applicant: The Board of Regents of the University of Texas System Austin, Texas 78701 (US)	(72) Inventor: MONSON, Nancy Dallas, Texas 75390 (US) (74) Representative: Rückerl, Florian  Dehmel & Bettenhausen Patentanwälte PartmbB Herzogspitalstraße 11 80331 München 80331 München (DE)