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EP 4 739 714 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24838715.1 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) A61P 35/02(2006.01) C12N 5/10(2006.01) C07K 16/46(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/02; A61K 40/31; A61K 40/11; A61K 40/4202; C07K 16/2866; C07K 2317/569; C07K 2317/92; A61K 2239/48 (86) International application number: PCT/CN2024/103875 (87) International publication number: WO 2025/011462 (16.01.2025 Gazette 2025/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 07.07.2023 WO PCT/CN2023/106254 (71) Applicant: Overland Therapeutics (US) Inc. Jingan District, Shanghai 200070 (CN)	(72) Inventors: LAN, Weijie Shanghai 200070 (CN) LI, Weimin Shanghai 200070 (CN) LI, Hongtao Shanghai 200070 (CN) HU, Yunfeng Eric Shanghai 200070 (CN) GUAN, Sihui Shanghai 200070 (CN) (74) Representative: Gleiss Große Schrell und Partner mbB  Leitzstraße 45 70469 Stuttgart 70469 Stuttgart (DE)